If you are using the Dectalk Express with Speakup, you can't use it with Emacsspeak at the same time because Speakup takes over the serial port and makes it not exist to the kernel. You'll have to add an entry to Lilo that boots your system and passes "speakup_synth=none." Then, boot with that entry when you want to use Emacsspeak. Alternately, use a different synthesizer for Emacsspeak from Speakup. For example, Via Voice Outloud with Emacsspeak and the Dectalk Express with Speakup. Good luck.