Chad, Himanshu Before I bisect or go chase changes, wanted to reach out because the driver seems to be the same version. Perhaps this is a PCIE change in the kernel for 4.10 affecting the load. Its the same targetLIO server I have been using for a long time with 4.9 27:00.0 Fibre Channel: QLogic Corp. ISP2532-based 8Gb Fibre Channel to PCI Express HBA (rev 02) With 4.9 I have no issues loading the driver for my targetLIO server. (DL380G8) # modinfo qla2xxx | more filename: /lib/modules/4.9.0.lobetcm+/kernel/drivers/scsi/qla2xxx/qla2xxx.ko firmware: ql2500_fw.bin version: 8.07.00.38-k license: GPL description: QLogic Fibre Channel HBA Driver author: QLogic Corporation srcversion: 94A8431A85BFF854B97B02D [ 8.906351] qla2xxx [0000:00:00.0]-0005: : QLogic Fibre Channel HBA Driver: 8.07.00.38-k. [ 10.014052] qla2xxx [0000:27:00.0]-001d: : Found an ISP2532 irq 106 iobase 0xffffadce989a1000. [ 10.455108] scsi host4: qla2xxx [ 10.460206] qla2xxx [0000:27:00.0]-00fb:4: QLogic QLE2562 - PCI-Express Dual Channel 8Gb Fibre Channel HBA. [ 10.460215] qla2xxx [0000:27:00.0]-00fc:4: ISP2532: PCIe (5.0GT/s x8) @ 0000:27:00.0 hdma+ host#=4 fw=8.03.00 (90d5). [ 10.460545] qla2xxx [0000:27:00.1]-001d: : Found an ISP2532 irq 110 iobase 0xffffadce989a9000. [ 10.662120] scsi host5: qla2xxx [ 11.007841] qla2xxx [0000:27:00.1]-00fb:5: QLogic QLE2562 - PCI-Express Dual Channel 8Gb Fibre Channel HBA. [ 11.007849] qla2xxx [0000:27:00.1]-00fc:5: ISP2532: PCIe (5.0GT/s x8) @ 0000:27:00.1 hdma+ host#=5 fw=8.03.00 (90d5). Rebooting on the same server with 4.10 fails to load Linux 4.10.0+ # modinfo qla2xxx | more filename: /lib/modules/4.10.0+/kernel/drivers/scsi/qla2xxx/qla2xxx.ko firmware: ql2500_fw.bin version: 8.07.00.38-k license: GPL description: QLogic Fibre Channel HBA Driver author: QLogic Corporation srcversion: 939E0595E8A3C2E1BE94392 [ 8.754040] qla2xxx [0000:00:00.0]-0005: : QLogic Fibre Channel HBA Driver: 8.07.00.38-k. [ 9.979523] qla2xxx [0000:27:00.0]-001b: : BAR 3 not enabled. [ 10.201268] qla2xxx [0000:27:00.0]-001d: : Found an ISP2532 irq 110 iobase 0xffffacbf189b1000. [ 10.407865] scsi host5: qla2xxx [ 10.444281] qla2xxx: probe of 0000:27:00.0 failed with error -22 [ 10.444519] qla2xxx [0000:27:00.1]-001b: : BAR 3 not enabled. [ 10.444522] qla2xxx [0000:27:00.1]-001d: : Found an ISP2532 irq 110 iobase 0xffffacbf189b9000. [ 10.645932] scsi host5: qla2xxx [ 10.682233] qla2xxx: probe of 0000:27:00.1 failed with error -22 Thanks Laurence