After updating to a 5700G APU from a 2400G on my B450 board I am not able to access i2c interfaces which is a blocking issue to use OpenRGB on the DRAM and motherboard RGB controller (I am one of the developers of OpenRGB). I have opened an issue with the distribution that I am using and multiple other users are seeing the same issue but I have not seen any updates on the issue or request for more details so I am afraid that it has just gone into the void. Full details here: https://bugs.launchpad.net/bugs/1950062 I see the same issues when using the i2c-tools as well when I am trying to read the DRAM so following the man page I would like to report a bug using the i2c-tools with AMD Cezanne APU's. Thanks for looking into this. Regards, TheRogueZeta