It seems as though it should be possible to use Gimp with two mice (or similar devices) to some advantage, using them to control different tools, using different settings. With AlwaysCore and the Xinput extended devices disabled (probably a common setup) you get what you'd expect - more physical devices sharing the same physical pointer and Gimp tools. Of course, this isn't really using two mice effectively. However with the extended device enabled, Gimp's behaviour (or is this GTK+ / XFree behaviour?) breaks down. Gimp can no longer properly detect the core cursor (you can't draw with it) and the additional mouse seems to always generate mouse down events at the origin, making it quite unusable. I started investigating this before, but didn't have a permanent setup where I could reproduce it. Now I do, so if anyone has any pointers or advice I'd appreciate it. Nick.