On May 28, 2015, the U.S. Food and Drug Administration approved Rapamune (sirolimus), to treat lymphangioleiomyomatosis (LAM),
a rare, progressive lung disease that primarily affects women of
childbearing age. This is the first drug approved to treat the disease. LAM is characterized by an abnormal growth of smooth muscle cells that
invade lung tissues, including the airways, and blood/lymph vessels that
cause destruction of the lung, resulting in airflow obstruction, and
limiting the delivery of oxygen to the body. Read more
|