Now here's the thing: Some weeks ago Proxmox upgraded from kernel 4.13 to 4.15. Since then I'm getting slow requests that cause blocked IO inside the VMs that are running on the cluster (but not necessarily on the host with the OSD causing the slow request). If I boot back into 4.13 then Ceph runs smoothly again.
This is PTI, I think. Try to add "noibrs noibpb nopti nospectre_v2" to kernel cmdline and reboot.
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