Fwd: High IOWait Issue

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Hi guys,
We are running a production OpenStack backend by Ceph.

At present, we are meeting an issue relating to high iowait in VM, in some MySQL VM, we see sometime IOwait reaches  abnormal high peaks which lead to slow queries increase, despite load is stable (we test with script simulate real load), you can see in graph.
https://prnt.sc/ivndni

MySQL VM are place on Ceph HDD Cluster, with 1 SSD journal for 7 HDD. In this cluster, IOwait on each ceph host is about 20%.
https://prnt.sc/ivne08


Can you guy help me find the root cause of this issue, and how to eliminate this high iowait?

Thanks in advance.

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