Error 451 when clients try to send emails

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Hi Everyone.  I am trying to gifure out why I am getting a 451 error when clients are trying to send email:

Client error:
Task 'mail.csdsinc.com - Sending' reported error (0x800CCC6A) : 'Your outgoing (SMTP) e-mail server has reported an internal error. If you continue to receive this message, contact your server administrator or Internet service provider (ISP).  The server responded: 451 mail server temporarily rejected message (#4.3.0)'


Here is a tail of my smtp log. 

@4000000047586d0f1cf5eae4 simscan: connect error 2
@4000000047586d0f1d36b4d4 connect(): Connection refused
@4000000047586d0f1d3e6594 qmail-smtpd: qq soft reject (mail server temporarily rejected message (#4.3.0)): MAILFROM:<removed to protect the innocent@@ edgemore.com> RCPTTO:removed top protect the innocent@xxxxxxxxxxx

Clam & Spam logs are normal.



Any ideas?


Thanks,

Ed
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