I am currently running
Centos 4.3
postfix-2.2.10-1.RHEL4.2
mailscanner-4.57.6-1
Your OS is out of date, but not terribly in the grand scheme of
things. This list probably remembers running CentOS 4.3 for quite a
bit and it was rock solid. I'd start with the SMTP error message.
Try to be as specific as possible when posting to lists. If the SMTP
error is your symptom, give us the EXACT smtp error. This may simply
be a problem where your system hit a "default install" performance
ceiling and/or ran out of resources. Errors of this nature usually
just require tweaking the config.
Regards,
Ken
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