MMWR Vol. 62 / Early Release

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Title: MMWR Vol. 62 / Early Release

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Early Release
Volume 62, Early Release
May 7, 2013

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Testing for HCV Infection: An Update of Guidance for Clinicians
and Laboratorians
 
In the United States, an estimated 4.1 million persons have been infected with hepatitis C virus (HCV), of whom an estimated 3.2 million are living with the infection. New infections continue to be reported particularly among persons who inject drugs and persons exposed to HCV-contaminated blood in health-care settings with inadequate infection control. In 2012, CDC amended testing recommendations to include one-time HCV testing for all persons born during 1945–1965 regardless of other risk factors. CDC is issuing this update of guidance because of
1) changes in the availability of certain commercial HCV antibody tests, 2) evidence that many persons who are identified as reactive by an HCV antibody test might not subsequently be evaluated to determine if they have current HCV infection, and 3) significant advances in the development of antiviral agents with improved efficacy against HCV.
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