MMWR Vol. 59 / Early Release

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Title: MMWR Vol. 59 / Early Release

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MMWR Weekly
Early Release
Volume 59, Early Release
June 2, 2010

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Preliminary Results: Surveillance for Guillain-Barré Syndrome After Receipt of Influenza A (H1N1) 2009 Monovalent Vaccine — United States, 2009–2010
Guillain-Barré syndrome (GBS) is an uncommon peripheral neuropathy causing paralysis and in severe cases respiratory failure and death. In rare cases, GBS can follow vaccination. To monitor influenza A (H1N1) 2009 monovalent vaccine safety, various federal surveillance systems, including CDC’s Emerging Infections Program (EIP), are being used. Preliminary results from an analysis in EIP comparing GBS patients who did and did not receive 2009 H1N1 vaccination revealed data, which if confirmed by end-of-surveillance analysis, would correspond to 0.8 excess cases of GBS per 1 million vaccinations, a rate similar to that found with seasonal influenza vaccines.
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