curl
http://123.456.7.543 (example ip address)
curl: (7) Failed to connect to 123.456.7.543 port 80: Connection refused
"Connection refused" means that your apache service is not bound to port TCP/80, it's down, or your routing send HTTP traffic to another host where apache is not installed.
Check if apache httpd is up and running, check if it's working on port 80 and also check your routing.